https://pubmed.ncbi.nlm.nih.gov/14993360/
Cytokines May Be Bad
Cytokines “… may be “bad” when their expression causes inflammatory diseases, such as the role of tumor necrosis factor α in rheumatoid arthritis or asthma and Crohn’s disease.” –PubMed.gov
Cytokines: The Good, the Bad, and the Deadly
https://pubmed.ncbi.nlm.nih.gov/26015504/
Neuroinflammation and Cytokines in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Critical Review of Research Methods
https://www.frontiersin.org/articles/10.3389/fneur.2018.01033/full
Benegene Study Results for ME/CFS
Apparently the bioavailability depends on it being thermally-stabilized oxaloacetate. BenaGene is one of the few supplements that is. Jubilance is another brand, although its marketed for PMS.
Oxaloacetate Treatment For Mental And Physical Fatigue
Results: Approx. a 25% improvement.